The Medico-Dental Building sits on the hulls of two abandoned ships. Despite its name, it was built as a warehouse for wine, tobacco and coffee, which perhaps indicates changing fashions in how to live a healthy life.

Other individually designated landmarks in this historic district are:

• Bank of Lucas, Turner and Company
• Belli Building
• Columbus Savings Bank
• Drexler-Colombo Building
• First Jewish Religious Services
• Freemasons Site
• Fugazi Bank Building
• Genella Building
• Ghirardelli Building
• Ghirardelli Annex
• Golden Era Building
• Grogan-Lent-Atherton Building
• Hotaling Building
• Hotaling Annex East
• Hotaling Annex West
• Hotaling Stables
• Mouline Building
• Old Ohio Street Houses
• Solari Building East
• Solari Building West
• Yeon Building